NAFTIZIN (Naphthyzinum). 2 - (a-Naftilmetil) - imidazoline nitrate.

     Nitrate (or the hydrochloride) produced abroad under the title : Sanorin, We nil, Imidin, Naphazolini nitras, Naphazoline nitrat e, R rivin, Rhinazin, Sanorin e et al.

     White or white with a yellowish sheen crystalline powder. It is soluble in water, soluble in alcohol.

     On chemical structure differs from Naphazoline noradrenalina, mezatona, fetanola ', but, like these compounds, it provides a adrenomimeticheskoe-operation. Compared with noradrenalinom mezatonom and is a long narrow peripheral vascular diseases. It increases blood pressure, increased momentum.

     In connection with sosudosuzhivayuschimi properties Naphazoline to inflict on the mucous membranes has anti-inflammatory effect of (anti). In rhinitis nasal breathing easier, reducing the flow of blood to the venous sine.

     Applied primarily in acute rhinitis, as well as to facilitate rinoskopii with pneumonia doctor cavities, to stop bleeding nose, with allergic conjunctivitis. It may also be used to slow down the intake mestnoanesteziruyuschih substances.

     In rhinitis impose adult 1 - 2 drops of 0.05-0.1% 0.1% solution or emulsion 2 to 3 times a day. Children from 1 year to designate 1 - 2 drops of 0.05% or 0.025% solution. Children babies for the opportunity to appoint Naphazoline overdose is not recommended. When bow krovotecheniyah use tampons, soaked 0.05% solution. When conjunctivitis give konyunktivalny bag 1 - 2 drops 0.05% solution.

     Not recommended Naphazoline, like other sosudosuzhivayuschie drugs for chronic rhinitis. If, however, Naphazoline use long, it should be borne in mind that sosudosuzhivayuschy effect gradually decreases (tahifilaksii phenomenon), it is recommended after 5 to 7 days of a break for a few days.

     For elongation of local anesthetics applied to the surface anesthesia, adds 2 to 4 drops of 0.1% aqueous naftizina to 1 ml anaesthetic substance.

     Naphazoline contraindications with hypertension, tachycardia, expressed atherosclerosis.

     Method of issuance : 0.05% and O.1% solutions in bottles of 10 ml.

     Storage : List B. In the dark spot.

     Abroad produced product "Sanorin (Sanorinum) - white emulsion containing 0.1% naftizina (nafazolina).

     Emulsion sosudosuzhivayuschy has more effect than the aqueous solution. When single backfilling nose effect (decrease swelling of the mucous membrane nose) lasts about 2 hours

     Applied with rhinitis (primarily acute), hay fever, conjunctivitis, as well as to facilitate rinoskopii. Buried in a bow at 1 to 2 drops of 2 - 3 times a day.

     Precautions and contraindications are the same as for naftizina.

     Product : in bottles of 10 ml.

     Storage : at a temperature of  +10 to +25  'C in a dark place (protection against freezing).

  'The structure naftizina (like galazolina) are similarities with the structure simpatomimeticheskih amines for apparently linking them with adrenoretseptorami.

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