NATAMITSIN (Natamycin).

     Stereoisomer 22-[(3-amino-3, 6-didezoksi-? -D- Mannopiranozil) Oxy] trioksi-12- metil-10- -1,3,26 - oxo-6-11.28 trioksatritsiklo [22. 3.1.0./5.7] oktakoza-8, 14,16,18,20 pentaen-25- - carboxylic acid.

     Synonym : Pimafutsin, Pimafucin.

     Polienovy antibiotic.

     Powder white or cream color. Nerastvorim in water, soluble in glacial acetic acid and dimethylformamide, poorly soluble in methyl alcohol. Sensitive to light.

     Active in yeast (Torulopsis, Rhoduturola) drozhzhepodobnyh fungi (Candida), dermatomitsetov (Trichophyton, Microsporum, Epidermophyton), other pathogenic fungi (Aspergillus, Penicillium), as well as gonnorrhoea.

     Not absorbed from the digestive tract, skin and mucous membranes.

     Assign to defeat fungal skin and mucous membranes, including acute and psevdomembranozny atrofichesky candidiasis after antibiotic therapy, and glyukokortikosteroidami cytostatica, genital candidiasis, otomikozy, candidiasis the skin, nails and ulcers, vaginitis, vulvity, dermatomycosis etc. Using well as trichomoniasis.

     Applied interior and local.

     Inside appoint (with candidiasis bowel) for adults 0.1 g four times a day during one week, the children - 2 times a day.

     In dermatomycosis to affected areas to cause skin cream or suspensions, with otomikozah-cream once or several times a day over 10-14 days; When vaginitis impose intravaginalno 1 jobs during 3-6 days, with their obstinate course also appoint the pill ( 1-4 times daily for 10-20 days).

     Possible side effects : when ingestion, nausea, vomiting; While local application-burning feeling.

     Contraindications : porphyria.

     Method of issuance : pills to 0.1 g (N. 20); For vaginal suppositories 0.1 g (N 3); 2% cream in tubes of 30 grams; 2.5% Suspension for external use in vials of 20 ml .

     Storage : List B.

     Pimafukort (Pimafucort). Ointments, cream and lotion, 1 g (ml) which natamitsina and hydrocortisone to 0.01 g (10 mg) and the neomycin 0.0035 g (3.5 mg).

     Applied infected with bacteria or fungi surface Medicine (cause for the affected areas of skin 2-4 times a day for 2-4 weeks).

Materials allowed to copy only with the active hyperlink to the handbook of medicines