NITRAZEPAM (Nitrazepamum). 7 - Nitro-2 - 3 digidro-5- phenyl-1 H-1, 4-benzodiazepin-2- it :

     Synonyms : Mogadon, Neozepam, Radedorm, Eunoktin, Apodorm, Benzalin, Calsmin, Dormicum, Dumolid, Epibenzalin, Epinelbon, Eunoctin, Hipnax, Hipsal, Insomin, Livetan, Magadon, Mitidin, Mogadan, Mogadon, Nelbon, Neozepam, Nitrenpax, Nitrodiazepam, Pacidrim, Pacisyn, Radedorm, Serenex, Somitran, Sonipam, Sonnolin and others.

     Light yellow or light yellow with a greenish white crystalline powder. Almost nerastvorim water malorastvorim in alcohol and ether.

     On chemical structure and pharmacological properties Nitrazepam close to the group of benzodiazepine tranquilizers (see) stukturnoy distinctive feature is the presence nitrazepama nitrogroup (NO) in regulation 7 benzodiazepinovogo nucleus.

     Like other derivatives benzodiapezina, Nitrazepam has trankviliziruyuschee, acid (protivotrevozhnoe) miorelaksantnoe (muscle relaxation), protivosudorozhnoe act oppressing conditional reflexes, suppresses polisinapticheskie spinal reflexes. The distinguishing feature is its expressed nitrazepama of sleeping pills.

     Influenced nitrazepama increase the depth and duration of sleep. Sleep usually comes after 45 minutes. after taking the drug and lasts 6-8 hours

     Nitrazepam applied to various kinds of sleep disorders, as well as the nervousness of different genesis and Psychopathy dominated by anxiety. In combination with other narcotic drugs or psychotropic medication designate sick schizophrenia, manic depressive (in Manic and gipomaniakalnoy phase), with some organic defeat CNS (trauma disorders of cerebral circulation), as well as edema cravings with chronic alcohol syndrome.

     As a means of soothing and protivosudorozhnoe Nitrazepam together with convulsants drugs designate epilepsy patients. The drug is also used in anaesthetics practice for sedation and aftercare period.

     Is Nitrazepam inside; As relief funds for half an hour so of sleep. Under the dose for adults is 0,005 - 0,01 g (5 - 10 mg); For children under the age of 1 year-0.00125 0.0025 g (1, 25, 2, 5 mg), 1-5 years 0,025 - 0,005 grams (2, 5, 5 mg); 6-14 years - 0,005 grams (5 mg). Those older appoint 0.0025 - 0.005 g (2, 5, 5 mg). The maximum single dose of a pain for adults is 0.02 g (20 mg). As a tranquilizer and protivosudorozhnogo means Nitrazepam use 2 to 3 times a day for 0,005 - 0,01 g (5 - 10 mg); If necessary, as a single dose drug protivosudorozhnogo funds can be improved. Higher daily doses of 0.03 g (30 mg). In exchange nitrazepama treatment duration of 30 to 45 days. In some cases, the duration of treatment may be extended.

     In applying nitrazepama, oso6 depth in high doses, can daily mood, feeling weak, mud, violation of traffic coordination, headache, oglushennost, dizziness, in rare cases, nausea, tachycardia, rash, skin allergic reactions. In most cases, these side effects have been observed in weak and elderly patients. In these cases, we must reduce the dose or stop medication.

     Nitrazepam contraindicated in pregnancy, especially during the first 3 months in infants, liver and kidney diseases in breach of their duties. In connection with nitrazepama depressing effect on the speed of reaction and attention should not be appointed during the transport drivers and others whose work requires quick mental and physical reactions.

     During treatment nitrazepamom no admission of alcohol. At the same time appointment nitrazepama to analgesics and other neurotropic drugs should take into account the possibility of strengthening them.

     Product : pills to 0,005 grams (white with zheltovatozelenovatym shade) in a package of 20 pieces.

     Storage : List B. In the dark spot.

Materials allowed to copy only with the active hyperlink to the handbook of medicines