NEW SHPA (No-Spa) *. 1-(3, 4-Dietoksibenziliden) -6, 7-dietoksi-1, 2, 3, 4-tetrahydroisoquinoline hydrochloride.

     Synonyms : Drotaverinum, Drotaverine hydrochloride, Deprolen, Dihydroethaverine, Nospan, Nospasin, Tetraspasmin.

     Crystalline substances light amber odourless. Mg in water and alcohol. On chemical structure and pharmacological action very close to papaverinu has a stronger and longer spasmolytic activity.

     Applied with stomach cramps and bowel, spastic constipation, stroke and chronic urolithiasis, gastric ulcers and duodenal ulcers (preferably in combination with holinolitikami), sometimes with peripheral vascular spasm (endarteriit etc.).

     Is the inside of 0,04 - 0,08 g (1 - 2 pills) 2 - 3 times a day. If necessary, impose the same dose (2 to 4 mL of 2% solution) intramuscularly. In attacks liver and kidney cramps and strokes are 2 to 4 mL of 2% solution intravenously (slowly!) . In violation of peripheral blood (obliteriruyuschy endarteriit) happened vnutriarterialno (slowly!) .

     Children designate smaller doses of age (1 / 4, 1 / 2 - 2 1 pill twice a day).

     The drug is usually well. When parenteral a possible sense of warmth, dizziness, rapid heartbeat, sweating. An allergic skin cases.

     Method of production : tablets of 0.04 grams in a package of 100 pieces; 2% solution in ampoules of 2 ml (0.04 g) in a package of 5 or 50 vials. Storage : List B.

     Nikoshpan (Nicospanum) *. Combined product, which includes a new spa and nicotinic acid.

     The combination of these substances provides increased sosudorasshiryayuschy effect (see Nicotinic acid). On the basis of the product is close to nikoverinu (see).

     Applied vascular spasm in the brain and peripheral circulatory violations (peremezhayuschayasya limp, trombangiit etc.).

     Assign inside of 1 - 3 pills a day (after eating), or 1 2 ml (1 / 2 to 1 vials) of the skin or intramuscularly 1 to 2 times a day. If necessary, enter slowly in the vein 1 ml. If peripheral circulatory disorders (obliteriruyuschy trombangiit) introducing (slowly) in the femoral artery of 1 - 2 ml.

     In applying nikoshpana possibly temporary Blush person, then the entire body, a sense of warmth. These phenomena are expressed particularly in the employment drug and shock associated with the pharmacological action of the drug components (see Niacin, New spa, as well as pills "Nikoverin").

     Method of issuance : pills to 0,078 g (78 mg) new shpy and 0,022 g (22 mg) of nicotinic acid; In ampoules of 0.0642 g (64 mg, 2) new shpy and 0.0176 g ( 17, 6 mg), nicotinic acid (2 mL).

     According to the pill "Nikoverin (see) very close to nikoshpanu.

     Storage : List B.

     Bishpan (Bis's num) *. Combined product, produced in the form of tablets containing 0.06 g (60 mg) new shpy and 0,005 grams (5 mg) holinoliticheskogo drug izopropamida (2, 2-difenil-4- aminobutiramida mode).

     Applied with cramps bowel, spastic colitis, giperatsidnom acute and chronic gastritis, gastric ulcer and duodenal ulcer, holetsistopatii, cramps disorders and other diseases involving smooth muscle cramps internal organs.

     Assign inside adult acute cases of 1 - 2 - 3 2 pills twice a day; In chronic cases, one pill 2 - 3 times a day for 3 to 4 weeks.

     Contraindications : hypertrophy prostate gland and glaucoma (especially zakrytougolnaya form).

     Storage : List B.

     Produced in Hungary.

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