NORETISTERON (Norethisteronum). Etinil a 17-b-17-K oksi-4- estren- it, or a 17-nortestosterone etinil-19-.

     Synonyms : Norkolut, Etinilnortestosteron, Aethynilnortestosteron, Anovule, Anzolan, Dianor, Fortilut, Gestest, Hormoluton, Micronor, Noralutin, Norcolut, Norethindrone, Norfor, Norgestin, Noridel, Norluten, Norlutin, Norluton, Norprogen, Primolut N Santalut and others.

     The structure is close to etinilestradiolu norethisterone. Is the latter a ketonovoy Group (instead of hydroxyl) to C double bond in the position of 4 - 5 Ring A.

     Norethisterone is well vsasyvayuschimsya oral gestagenom. The maximum concentration in plasma is found in 1 - 2 hours after taking the drug.

     Indications for use mainly the same as for other gestagenov (see Progesterone, Pregnin), including dysfunctional uterine bleeding skills, pre syndrome, menstrual disorders, as well as endometriosis, glandulyarnaya cystic hyperplasia of endometrium and others.

     Assign inside usually dose 0,005 - 0,01 g (5 - 10 mg) per day (1 - 2 pills).

     In pre syndrome and menstrual irregularities appoint 1 - 2 pills a day, starting with the 16-day cycle to a 25-day. In krovotecheniyah dysfunctional uterine hyperplasia and cystic glandulyarnoy endometrium appoint one-two pills a day for 6 to 12 days. To prevent a recurrence of taking the same dose for the period from 16 th to the 25-day cycle (typically with Estro gene product).

     In endometriosis designate long-term (within six months) and 1 tablet a day from the 5 th to the 25 th day of the cycle or at the 1 / 2 tablets from the 5-day cycle, and gradually increasing the dosage to 1 / 2 tablets every 2 - 3 weeks for 4 to 6 months.

     When menopause syndrome appoint one pill per day (length), together with oestrogenic drug, such etinilestradiolom dose of 0.025 mg, 0.05 (25-50 µ g / day).

     In all cases the dose noretisterona be collected individually depending on the nature of the disease, the effectiveness of treatment and re nosimosti drug.

     The application may be nausea, allergic reactions (skin rashes, etc.), parestezii, increased fatigability and others.

     Contraindications : Progesterone see.

     Product : pills to 0,005 grams (5 mg).

     Storage : in a dry, cool, the dark spot.

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