OFLOKSATSIN (Ofloxacinum). Fluorine-9-2, 3-digidro-3- metil-10- (4-methyl piperazinil) -7 - oxo-7 H-pirido / 1, 2, 3-de / 1, 4-benzoksazinkarbonovaya acid.

     Synonyms : Tarivid, Flobocin, Mefoxacin, Ofloxacin, Oflozet, Oxoldin, Tabrin, Tarivid, Viseren, Zanocin.

     Crystalline substances slightly yellowish, odourless, bitter taste. Few rastvorimo in water and alcohol.

     On chemical structure is piperazinilzameschennym ftorhinolonom with more <built> metilzameschennym oksazinovym nucleus.

     Like other Fluoroquinolones, ofloxacin a broad spectrum antibacterial action. Affects mostly gram bacteria. Effective against microorganisms resistant to most antibiotics and sulfanilamidam. It has bactericidal activity.

     Effective with the ingestion. Quickly and almost entirely (over 95%) absorbed from the gastrointestinal tract, comes in high concentrations in organs and tissues, and in the sputum, saliva, bile, skin, tissue and secret prostate gland. Peak concentrations in plasma nablyudatsya through PC-60 minutes; The half-about 6 to 7 hours The drug is metabolized little; 75-90% of urine output, even after receiving a single product found in urine for 20 to 24 hours

     Applied ofloxacin infection in the respiratory tract, ear, throat, nose, skin, soft tissue, osteomyelitis, infectious eabolevaniyah : abdominal, kidneys, urinary tract, prostate, gynecological infectious diseases, gonorrhea.

     There is evidence of activity ofloxacin (tarivida) against Mycobacteria tuberculosis and feasibility of their use in treatment of tuberculosis.

     Assign inside adults in the following doses : with respiratory tract infections, skin and soft tissues (wounds Furuncles, carbuncles, phlegmon, etc.) and infectious diseases of the abdominal cavity, the upper urinary tract-how to 0.2 g (1 tablet) 2 times a day; infection with the bones and joints-to 0.2 - 0.4 g (1 - 2 tablets), 2 times a day; when Urethritis and prostate-by 0.3 - 0.4 g, 2 times a day.

     In heavy infections and other respiratory tract infections heavy dose increased to 0.3 - 0.4 grams per day.

     Is pill tarivida not liquid, with a small amount of water before or after a meal.

     Treatment, and the application of other chemotherapy drugs, are disappearing signs of the disease and in the next 2 to 3 days or more. Treatment usually 7 to 10 days. In normal cases, treatment may be shorter. You can not take medication over four weeks.

     The drug is usually well. In some cases, there are allergic reactions (skin itch, rash); Possible development of oedema person voice; Anorexia, abdominal pain, nausea, vomiting, diarrhea; Sleep disorders, headache, anxiety, the general oppression; Changing images of blood (radiation , agranulotsitoz, thrombocytopenia). In rare instances the perception of smell and taste.

     In applying ofloxacin, as well as other ftorhinolonov should not be subjected to ultraviolet rays due to the potential for skin photosensitization.

     Contraindications : Hypersensitivity to Moldova, epilepsy. Do not assign product pregnant, lactating women, children and adolescents with incomplete formation of the skeleton (15). In violation of kidney functions are normal dose first, and then reduce them in the light of creatinine clearance.

     We have to take ofloxacin while antatsidnymi means (including alkaline water) to avoid reducing effectiveness.

     Product : 0.2 grams of pills in a package of 10 pieces.

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