ORLISTAT (Orlistat).

     Synonym : Ksenikal, Xenical.

     The synthetic analogue tetragidrolipostatina, produtsiruemogo Streptomyces toxytricini.

     Ingibiruya stomach, intestinal and pancreatic lipase, triglycerides splitting blocks in the gut, resulting in a reduction of intake and blood flow in the system of free fatty acids and monoglitseridov. Thus, the product fundamentally different from anoreksigenov-not affect appetite and the intake of fats in the digestive tract.

     Once inside the system reaches the bloodstream, output gradually (within 3-5 days) with feces, mostly unchanged.

     The drug has a gipoholesterinemicheskoe and gipotriglitseridemichekoe action to improve glucose tolerance.

     Assign orlistat in the face of low-calorie diet (containing no more than 30% fat) in the dose of 0.12 g (1 capsule) three times a day, with each receiving food.

     The drug is relatively well postponed, but the side effects are sometimes difficult to use. In some cases likely to mandatory golden hair, flatulence, oily discharge from the bowel, incontinence Kala, flavour arterial hypertension.

     The drug is not suitable for chronic malabsorbtsii, cholestasis, pregnancy, breast-feeding, infant.

     Product : Capsule to 0.12 g (N. 21).

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