OKSIFEDRIN (Oxyfedrinum) *.

     DL-3- (b-a-Oksi- metilfenetilamino) -3 '- metoksipropiofenona hydrochloride.

     Synonyms : Ildamen, Miofedrin, Ildamen, Myofedrin, Oxifedrin.

     Chemically belongs to the group fenilalkilaminov and structure is the product of ephedrine (see), which is a metoksipropiofenonovoy instead of methyl groups in amino nitrogen atom.

     The drug has a partial agonisticheskoy activity to the heart-adrenoretseptoram, has a direct effect koronarorasshiryayuschee increases Oxytocics ability to attack without excessive increase in oxygen demand.

     Indications for use : stenocardia voltage (with infrequent attacks) with aetiology.

     Assign inside to 8 mg (0,008 grams), 3 times a day, with little effect on the 16 mg (32 mg) three times a day.

     Contraindications : Insertion inadequate to the phenomena of blood subaortalny stenoses. As the experimental data oksifedrin under certain conditions can have a direct effect on depressing attack that may be connected to the embargo ~-adrenoreceptor.

     Product : pills for 0,008 and 0,016 g (8 and 16 mg).

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