OKSIPROGESTERONA KAPRONAT (Oxyprogesteroni caproas).

     Pregnen-4- ol - a 17-glows - 3 kapronat 20, or a 17-pregnen oksi-4- -3, 20-17-glows peroxide.

     Synonyms : Gormofort, Caposten, Caprosteron, Capton, Delalutin, Depolut, Eslralutin, Hormofort, Hydroxyprogesterone caproate, Hydroxyprogesteroni caproas, Neolutin, Primolut-Depot, Progesteron-retard, Prolutin-Depot, Syngynon and others.

     White or white to slightly yellowish sheen crystalline powder. Almost nerastvorim in water, soluble in alcohol, fatty oils. a 17-Oksiprogesterona kapronat is a synthetic hormone similar to the yellow body-progesterone. The chemically different from proges terona that position with a balance of 17 Caproic acid. As air oksiprogesterona, oksiprogesterona kapronat more racks in the body than progesterone, is slower and has prolon girovanny effect. After a single intramuscular injection of oil solution oksiprogesterona kapronata it lasts from 7 to 14 days.

     On biological properties oksiprogesterona kapronat similar to progesterone. Applied with pathological processes, the lack of yellow body. Enter intramuscularly in the form of solution in oil.

     In order for prevention and treatment and began threatening to impose abortion on 0,125 - 0,25 g (1 - 2 12 ml, 5% solution) one day a week. Oksiprogesterona kapronat apply only in the first half of pregnancy.

     When amenorrhea (primary and secondary) designate oksiprogesterona kapronat directly after termination of oestrogen drugs; Entering 0.25 g once or in two installments.

     To treat dysfunctional uterine bleeding oksiprogeste party kapronat less convenient than progesterone, as well as its effect us shs slowly; Oksiprogesterona kapronatom may, however, be useful for normalization cycle. Recommended impose anti-dose 0,0625 0,125 grams (0.5-1 0 12 ml, 5% solution) at 20-22-day cycle.

     Oksiprogesterina kapronat also used in the treatment of cancer of uterus, breast and some other malignant tumors. Enter 25% solution of 3 - 4 ml intramuscularly every day or every other day for a long period (30-300 days).

     Product : 12, 5% (0,125 g) and 25% (0.25 g) solutions oksipro gesterona kapronata in oil in capsules containing 1 ml.

     Storage : List B. In the dark spot. Ampoules maintained at a temperature of not lower than C. In the case of fallout in the crystal vials, ampoules heated in boiling bath with shaking. If the crystals to disappear, and the solution will be transparent, and on cooling to 36 +-38 chips are not falling again, the solution to fit the application.

     Rp. : Sol. Oxyprogesteroni caproatis oleosae 12, 1 ml 5%

     D.t.d. N. in ampull 10.

     S. On January 1 ml intramuscularly once a week

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