PARATSETAMOL (Paracetamolum). Atsetaminofenol parameters.

     Synonyms : Opradol, Panadol, Ushamol, Abesanil, Acelifen, Acemol, Acetalgin, Acetaminophen, Acetaminophenol, Actasol, Algotropyl, Alvedon, Aminophen, Amphenol, Apagan, Apamide, Apanol, Biocetamol, Celifen, Cetadol, Cetanil, Chemcetaphen, Dapirex, Datril, Dexamol, Dimindol, Dolamin, Dolanex, Dolipram, Efferalgan, Erocetamol, Febridol, Febrinil, Febrinol, Fendon, Metamol, Minoset, Myalgin, Napamol, Naprinol, Nasprin, Nysacetol, Opradol, Pacemol, Panadol, Panadon, Paracinol, Paramol, Pyrenol, Pyrinazin, Rolocin, Tempramol, Tralgon, Tylemin, Tylenol, Ushamol, Valadol, Valgesic, Valorin, Volpan, Winadol and others.

     White with cream or white or pink shade crystalline powder. The easily soluble in alcohol, nerastvorim water.

     Paracetamol is chemically similar to fenatsetinu. It is a major metabolite, quickly formed in the body when fenatsetina admission; Apparently makes analgetichesky effect last. On Paracetamol has an activity does not differ significantly from fenatsetina; Fenatsetinu like, it has a weak antiinflammatory activity. The main advantages are lower paracetamol toxicity, reduced ability to cause metgemoglobina education. However, the drug can also cause side effects; In long-term use, especially in high doses, paracetamol can nefrotoksicheskoe and gepatotoksicheskoe effect.

     Paracetamol absorbed in the upper divisions of the bowel, is metabolized in the liver, kidneys allocated mainly.

     Indications for use are the same as for amidopirina and fenatsetina.

     Doses for adults 0,2 - 0,4 g per reception 2 to 3 times a day.

     Higher doses for adults inside : single 0.5 g daily 1, 5 g.

     Children aged 6 to 12 months to appoint 0,025 - 0.05 g, 2 - 5 years - 0.1 - 0.15 g, 6-12 years - to 0,15 - 0,25 g appointments 2 to 3 times a day.

     When using paracetamol should monitor liver function, the state of the haematopoietic system; Possible allergic reactions.

     Method of issuance : powder and pills to 0.2 g.

     Storage : List B. The well ukuporennoy packaging keeps out of the world : pills, in the dark place.

     Recently, the restriction of amidopirina and fenatsetina become relatively common use of paracetamol and medicines containing paracetamol combined form (in combination with acetylsalicylic acid, analginom, caffeine, codeine, etc.).

     Abroad paracetamol (panadol, panadon) produced in different medicinal forms : tablets, capsules, medicine, syrup, <<bubbly>> powders. There are a number of combined dosage forms containing paracetamol combined with caffeine, codeine and other drugs;

     The Republic of Korea issued a preparation Coolpain-S (kulpeyn-S; Kulpan-C) - tablets containing 0.5 grams of paracetamol and 0.25 g methionine.

     Rp. : Tab. Paracetamoli 0.2 N. 10

     D.S. At one tablet three times a day

     Rp. : Paracetamoli

     Ac. acetylsalicylici aa 0.25

     Coffeini natrio-benzoatis O, l

     M.F. pulv.

     D.t.d. N. 10

     S. He is the one powder 2 - 3 times a day

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