Pentagastrin (pentagastrinum)
PENTAGASTRIN (Pentagastrinum).
N-tert-b Butiloksikarbonil- alanil-L- triptofil-L- metionil-L- asparaginil-L fenilalanilamid (pentapeptid).
Synonyms: Acignost, Gastrodiagnost, Pentagastrin, Peptavlon.
White or white with a slightly yellowish tinge amorphous powder odourless. Virtually not soluble in water, very little soluble in alcohol.
It is a synthetic hormone similar digestive-gastrina. It has the ability to greatly stimulate the secretion of stomach. Apply as a catalyst for diagnosing digestive secretion of stomach illness (as defined secretory capacity and functions kislotoobrazuyuschey stomach see also Gistamin).
Implemented in the form of 0,025% solution. Enter under the skin at a rate of 6 µ g (0,006 mg) for 1 kg of body mass sick.
Since the introduction of the drug increased secretion after 5 - 10 minutes, reaching a maximum after 15 to 30 minutes and lasts for 1 hour or more.
Study digestive juice are usually every 15 min for 1 h or more.
With the drug may watering, nausea, kratkovremennnoe moderate decline in blood pressure, unpleasant feelings in the abdomen.
Application pentagastrina counter with circulatory insufficiency stage II-III, a heart rhythm irregularities expressed hypotension.
Form of: a solution in the ampoule containing at 0.5 mg (2 ml = 500 µ g product).
Storage: List B. In sheltered from the world scene with a temperature of 1 to 6 C.
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