PERITSIAZIN (Periciazine). Tsian-10- 2-[3-(4-oksipiperidino) - propyl] - fenotiazin.

      Synonyms: Neuleptil, Aolept, Apamin, Nemactil, Neulactil, Neuleptil, Periciazinum, Propericiazine.

      Like Thioridazine, belongs to the group piperidinovyh fenotiazina derivatives. These drugs are less severe than antipsihoticheskoy activity aliphatic and derivatives piperazinovye fenotiazina.

      Like other neuroleptic, Periciazine potentsiruet of drugs, sleeping pills and analgetikov. Has adrenoliticheskoy and relatively strong holinoliticheskoy activity; Protivorvotnoe have a strong effect.

      Antipsihotichesky effect peritsiazina combined with sedative without the stimulus component.

      Preparation is shown in the treatment of patients with psychotic, and with psihopatopodobnymi state. Especially effective for violations of conduct (especially in children), contact disorders. Decreases aggressiveness and the more lenient than aminazina, sedative effect is expressed weakness, delayed, postponed well.

      In a more selective than other Neuroleptics, normalizing influence on the conduct Periciazine received in the literature as <<corrector conduct>>.

      Assign Periciazine inside after eating. The dose for adults is first 5 - 10 mg / day; Then gradually increase (every 1 to 2 days to 10 mg) to obtain an optimal effect (usually up to 30-50 mg, and in some cases up to 70-90 mg / day).

      Daily dose given in 2 - 3 admission: morning 1/4- 1 / 3 daily allowance, the rest in prime time (on the possible development immediately).

 

      Children age and persons appointed from 5 mg / day, then gradually increase the dose to 30-10-20 mg per day. After enduring effect dose of the drug gradually, selecting individual dose supportive.

      In applying the drug may have allergic reactions, extrapiramidale violations, but they generally expressed less than aminazinom treatment.

      Method of issuance: Capsule to 0.01 g (10 mg) and 4% solution in vials (1 drop of 1 mg preparation); Drops in drug more convenient for use in pediatric practice.

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