FENAMIN (Phenaminum). d l-1- Fenil-2- aminopropana sulfate or d, l-b-fenilizopropilamina sulfate.

     Synonyms: Aktedrin, Alentol, Amphamine, Amphedrine, Amphethamini sulfas, Amphetamine sulfate, sulfate Benzedrine, Benzpropamin, Euphodyn, Isoamin; Ortedrine, Psychedrinum, Psychoton, Racephen, Raphetamin, Sympamin, Sympatedrine and others.

     The white crystalline powder bitter taste. Soluble in water (1:20 in the cold, the hot 1:3), little soluble in alcohol.

     Fenamin are synthetic compounds, derived fenilalkilamina. For some chemical structure and pharmacological properties (mainly on the impact on the peripheral sympathetic nervous system divisions), he is close to a group of drugs adrenaline.

     By building different from adrenaline and noradrenalina gidroksilov lack of aromatic cycle and alifaticheskoy chain, which makes it more resilience and, in addition, you can easily cross the blood-brain barrier to overcome; Extensive character alifaticheskoy chain (a methyl group in a position to-aminoacid) keeps its molecule oxidation of dezaminirovaniya monoaminoksidazoy.

     Through persistence in the body fenamina cuts and the effects are being hired him inside.

     Fenamin is a powerful stimulant agent. Enabling linked to the drug in large part to his influence on the part of the brain stem.

     In neyrohimicheskom mechanism of action fenamina major role played by his ability to cause the release of granules presinapticheskih nervous end noradrenalina and dofamina and encourage thus central noradrenergicheskie and more dofaminergicheskie receptors. He also has a small effect on the inhibition activity monoaminoksidazy and inhibits reverse takeover neyronalny dofamina and noradrenalina.

     Fenamin also has peripheral adrenergicheskoy activity (promotes a-and b-Adrenergic); He was reduced peripheral vascular, increased reduce heart, increasing blood pressure, relax Muscle bronchi, expand inside. These effects are more long, but expressed less than adrenaline.

     When dosing fenamin, reinforcing processes in the central institution, reduces the sense of fatigue, the overall incident has influence terms of improving sentiment, feeling tide forces, air, increasing efficiency, reducing the need for sleep.

     Fenamin and its analogues are weakening and shortening sleep caused by diet and drugs, which are sometimes called probuzhdayuschimi amines.

     The product has anoreksigennoy activity, ie reduced appetite and contributes to a faster offensive feelings saturation diet.

     Long time fenamin considered one of the main psychoactive funds. They are widely used to improve mental and physical performance, for the treatment of narcolepsy, depressive state, the effects of encephalitis and other diseases characterized by confusion, weakness, apathy, asthenia, with postentsefaliticheskom parkinsonizme (with holinoliticheskimi drugs).

     In recent years, the possible side events (violation higher nervous activity, increased blood pressure, relatively frequent paradoxical reaction-confusion and apathy rather than initiate, reduction of efficiency, etc.) and, more importantly, with regard to the possible development of habit and addiction have fenaminom using extremely rare.

     Assign fenamin inside adult for the 0,005 - 0,01 g (5 - 10 mg), 1 to 2 times a day. Effect of single reception lasts 2 to 8 h.

     Doses to be collected individually by the various sensitivity and portability. Of the body's drug appears slowly possible cumulative phenomenon.

     Fenamin should be applied with caution and only for medical reasons. When drug overdose can be dizziness, vomiting, nausea, loss of appetite, insomnia, tachycardia, arrhythmia.

     In the long unchecked use of possible heavy nervnopsihicheskie disorder until shizofrenopodobnyh Psychosis.

     When you receive fenamina afternoon may disrupt sleep.

     Contraindications to the use fenamina an elderly age, insomnia, the state of excitation, liver disease, hypertension, atherosclerosis, organic cardiovascular diseases.

     Form release: pills to 0.01 grams in a package of 10 pieces.

     Storage: A. In a list ukuporennoy packaging.

     Allow it to fall to the same restrictions as drugs.

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