Fepranon (phepranonum)


FEPRANON (Phepranonum). 1-Fenil-2- dietilamino-1- propanona hydrochloride.
     Synonyms: Abulemin, Amfepramone, Amfepramonum, Amphepramon, Anorex "Orto, Danulen, Diethylpropion, Dobesin, Keramm, Natorexic, Parabolin, Regenon, Tenuate, Tepanil etc.
     White or white with a slightly kremovatym white crystalline powder bitter taste. Easy soluble in water and alcohol.
     Fepranon be regarded as analogous fenamina, but especially chemical structure make some difference in pharmacological properties of these compounds.
     The product has anoreksigennoy activity. Relatively with fenaminom, fepranon incident has little impact on the central and peripheral little impact on adrenergicheskie structure, that is a little more selective anoreksigennym action.
     Indications for use fepranona is mainly exogenous (alimentarnoe) obesity; It can also be used in adipozogenitalnoy malnutrition (in combination with hormonal therapy), and hypothyroidism (with tireoidinom) and other forms of obesity. The treatment in combination with diet malokaloriynoy, if necessary with unloading days.
     Assign inwards in the form of tablets to 0,025 g (25 mg) 2 - 3 times a day for half an hour or hour before food (breakfast and lunch). With good portability and the lack of effective dose can be increased to four pills a day. The course of treatment 1, 5, 2, 5 months. If necessary to repeat courses intermittently 3 months.
     Fepranon generally well tolerated by. However, those with high sensitivity and overdose may cause irritability, insomnia, aridity in the mouth, nausea, diarrhoea or constipation and other side effects. In appointing people with drug cardiovascular diseases and hypertonia needed care.
     Treatment should be under close medical supervision.
     The product contraindications in pregnancy, are coming form hypertensive disease expressed violations brain and coronary circulation, heart attack Chavez, thyrotoxicosis, glaucoma, and pituitary tumors ?, sugar diabetes, high nervous excitability, epilepsy, psychosis, severe violations of sleep. It should appoint a drug patients receiving monoaminoksidazy inhibitors (see Nialamid).
     Not rekomendueteya take the drug in the second half of the day (to avoid violations of sleep).
     Form release: pills to 0,025 (25 mg) in a package of 50 pieces.
     Storage: List A. In a dry, sheltered from the world scene. Allow it to fall only on medical prescription.

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