FTOROTAN (Phthorothanum). 1, 1, 1-chloro Triftor-2- brometanyu.

     Synonyms: Galotan, Narkotan, Fluotan, Anestan, Fluctan, Fluothane, Ftorotan, Halan, Halothane, Halothanum, Narcotan, Rhodialotan, Somnothane.

     Discoloured, transparent, mobile, easy to fly with a liquid smell, smell like chloroform, and pressing sweet taste. The density of 1,865 - 1,870. Boiling point (distillation) + 49-51 C. Little soluble in water (0.345%), mixed with anhydrous alcohol, broadcast, chloroform, trichloroethylene, oils. The ratio of oil / water 330. Elasticity pair with a temperature of + 20 C is 241, 5 mm Art. Art.

     Halothane not lit and not see paragraph. His pair mixed with oxygen and nitrogen oxide in the ratio applied for anaesthesia, vzryvobezopasny that it is a valuable properties when used in the current operation.

     Under the light of Halothane slow decomposition, so it remains in the glass bottle orange; Add to stabilize thymol (0.01%).

     Halothane a powerful narcotic tool that allows its own (oxygen or air) for surgery under anaesthesia or as a component of the combined anaesthesia in combination with other drugs, primarily nitrogen oxide.

     Farmakokineticheski Halothane vsasyvaemostyu differs slightly from the respiratory tract and the rapid disbursement of Light unchanged to; Only a fraction ftorotana metabolized in the body. The product provides rapid drug operation, ceasing shortly after inhalation.

     For the introduction of anaesthesia ftorotana start with a concentration of 0.5. % (oxygen), then for 1, 3, 5-min increase it to 3-to 4. %. To maintain surgical anaesthesia being applied concentration of 0,5-2. %.

     Using ftorotana consciousness usually shut down by 1-2 minutes after inhalation of vapours. After 3-5 minutes is a surgical stage anaesthesia. After 3 to 5 minutes after the start of ftorotana patients emerge. Narkoznaya depression completely disappears after 5 to 10 minutes, and after a short 30-40 min after prolonged anaesthesia. Excitement is rare and poorly expressed.

     Couples ftorotana not cause irritation mucous membranes. Significant changes in gas anaesthesia ftorotanom not happening; Blood pressure usually falls, in part due to the depressing effects of the drug on sympathetic ganglii and expansion periferichesknh receptacles. Selective nerve tone remains high, which creates conditions for arrythmia. To some extent Halothane has deprimiruyuschee effect on the heart. In addition, Halothane increased sensitivity Chavez to rest: Your introduction and noradrenalina during anaesthesia could cause ventricular fibrillyatsiyu.

     Halothane not affect kidney function; In some cases, possible violations of liver function with the advent of jaundice.

     Under ftorotanovym anesthesia can be different operational intervention, including abdominal and thoracic organs cavities, children and the elderly. Incombustibility enables applications to use during Operation electricity and rentgenoapparatury.

     Halothane suitable for use in operations of the thoracic cavity, as is mucous membranes irritation of the respiratory tract, oppressing secretion, relaxing respiratory musculature that facilitates artificial lung ventilation. Ftorotanovy anaesthesia can be used in patients bronchial asthma. Especially shows use ftorotana when it is necessary to avoid stress and the initiation of the patient (neurosurgery, oftalmohirurgiya etc.).

     Halothane part of the so-called azeotronnoy mixture consisting of two large part ftorotana and one volume of air. This mixture has a strong narcotic effect than air, and less severe than Halothane. Anaesthesia is slower than in the application ftorotana but faster than in the application of airtime.

     In anaesthesia ftorotanom be precisely and smoothly manage the flow of vapour. We must take into account the rapid changes in stages anaesthesia. So ftorotanovy anaesthesia with a special evaporator away from the circulation system. The concentration of oxygen in the mixture of asbestos should not be below 50%. For short-term transactions Halothane also sometimes used by regular masks for anaesthesia. When submitting ftorotana to mask the number 30 -- 40 drops per minute during stimulation lasts for about 1 minute, a stage surgical anaesthesia is usually 3 to 5 th minutes. As a rule, beginning with a mask on ftorotana at speeds of 5 to 15 drops per minute, and then rapidly increase the supply of 30 - to 50 drops per minute; For surgical anaesthesia being submitted to the 10-25 drops per minute. Apply Halothane via mask is not recommended for children.

     To avoid side effects associated with radiation nerve stimulation (aetiology, daily), patient before anaesthesia impose atropine or metatsin. For apoptosis preferable not to use morphine, and promedolom, which brings less selective nerve centres.

     If necessary, increase muscle relaxation preferably appoint Judge depolyarizuyuschego type of (ditilin); The application of drugs nedepolyarizuyuschego (competition) like last dose reduce to normal. Concentration ftorotana using muscle (when administered breathing) should not exceed 1 1 / 5 on. %. Ganglioblokatory designate smaller doses because they potentsiruetsya ftorotanom.

     In ftorotanom anaesthesia to the oppression sympathetic gangliev and expand peripheral vascular possible increased bleeding that requires a careful hemostasis, and if necessary to krovopoteri.

     Due to the rapid awakening after anaesthesia, patients may feel pain, so early application of analgesics. Sometimes in the postoperative period is typically (as a result of vessels and heat losses during operation). In such cases, patients need warming radiators. Nausea and vomiting are not usually occur, but should consider their appearance in connection with the introduction of analgesics (morphine).

     Ftorotanom anaesthesia should not be used in feohromotsitome in other cases where enhanced content in the blood adrenaline, and expressed hypertonia. Caution must be applied in patients with heart rhythm irregularities, and hypotension, organic defeat liver. In gynecological operations should be borne in mind that Halothane might tone down the uterine musculature and increased bleeding. Application ftorotana in OBGYN gynaecological practice should be limited to those cases where uterine relaxation is shown. Influenced ftorotana uterus decreases sensitivity to drugs, causing a decrease (alkaloids sporyni, oxytocin).

     In anaesthesia ftorotanom not apply Adrenaline and Norepinephrine avoid aritmy.

     It should be borne in mind that the people working with ftorotanom, can develop allergic reactions.

     Form of: a well ukuporennyh orange glass bottle for 50 ml.

     Storage: List B. In a dry, cool, sheltered from the world scene.

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