PIMOZID (Pimozidum). 1-(1-4, 4 - Bis (para-fluorophenyl) - butyl] -4 - piperidil) - benzimidazolinon.

     Synonyms : Orap (oral antipsihotik) Antalon, Norofen, Opiran, Oralep, Orap, Pimotid, Pirium.

     The white crystalline powder. Nerastvorim almost in the water.

     Is difenilbutilpiperidina derivatives; Structure side chain is close to benperidolu.

     On the spectrum of close to haloperidol, has expressed antipsihoticheskoe effect.

     Features of the drug is relatively long effects when administered. Step comes quickly, and the maximum effect is usually develops after 2 hrs, lasted about 6 hours and passes through 24 h.

     Applied Orap outpatient treatment for maintenance therapy in patients previously treated neyrolepticheskimi drugs. Convenient to use, as it does not have gipnosedativnogo action. In-patient and outpatient treatment used to treat schizophrenia, paranoidnyh states Disorders and neurotic condition with paranoidnymi traits. To treat aggressive and bringing in acute psychosis unsuitable because no psihomotorno- sedative action.

     Can be used in combination with other drugs neyrolepticheskimi. When severe mental illness to begin with the appointment of neuroleptic treatment provider gipnosedativnoe effect, and then gradually reducing the dose of the neuroleptic, go to a reception pimozida.

     Assign Orap inside to food in the form of pills. Initial dose for adults 0,001 g (1 mg) once a day, then gradually increase the dose. Average daily dose of 5 mg (8 mg); Take every day.

     When treating pimozidom may appear extrapiramidale disorder problems that take antiparkinsonicheskie funds. In the early days of treatment (primarily upon receiving previously designated Neuroleptics with sedative effect) may increase aggressiveness.

     The drug should not appoint women in the first three months of pregnancy.

     Product : pills to 0,001 g (1 mg) in a package of 50 pieces and 0,004 grams (4 mg) in a package of 20 pieces.

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