PIPERAZINE (Piperazinum).

     Diethylenediamine.

     Piperazine and its salts have protivoglistnoe effects on different types of nematodes, especially concerns ascariasis and enterobioz (ostritsami invasion). They operate as a sexually, and immature individuals of either sex.

     Piperazine was paralyzed muscles worms; Later they returned peristaltic movements bowel. In 1990, 95% of piperazine relieve the body of parasites, a second application can be achieved almost 100% deworming.

     Drugs piperazine quickly imbibed with the ingestion. Are mainly kidneys. They require no prior training or sick for a special diet. Laxatives funds designated only if propensity for constipation; Give them days piperazine evening reception.

     Drugs piperazine low dosage and side effects usually do not cause; Can be used in outpatient settings. Sometimes there are slight nausea, abdominal pain, headache skoroprehodyaschaya. When possible overdose muscle weakness, tremor. Patients who are violating excretory functions of the kidney may be neurotoxic effects.

     Contraindications : organic diseases of CNS.

     Piperazine main drug used as a means protivoglistnogo is piperazine adipate.

     , Piperazine adipate (Piperazini adipinas).

     Synonyms : Adipalit, Adiprazina, Entacyl, Entazin, Helmirazin, Heltolan, Nematocton, Nometan, Oxurasin, Piperascat, Piperazine adipate, Piperazinum adipinicum, Vermicompren, Vermitox And p.

     The white crystalline powder and odourless. Mg in water easily in the warm, almost nerastvorim in alcohol and ether.

     When treating drug ascariasis appoint two days to 2 times a day for 1 hour or later, 1 / 2 to 1 hour after a meal. Are the inside in the form of tablets in doses of 1 admission : Adults - 1 5-2, 0 grams (3 to 4 grams per day); Children under 1 year of 0.2 g (0.4 g / day) 2 to 3 years to 0.3 g (0.6 g / day), from 4 to 5 years to 0.5 g (1 g / day); from 6 to 8 years to 0.75 g ( 1, 5 g per day), from 9 to 12 years and 1 g (2 g / day), between 13 and 15 years - 1, 5 g (3 g / day). Children may be nominated in the preparation of 5% solution.

     You can also receive medication for one day : one from 0.4 to 4 grams (depending on age) or 2 times from 0.2 to 2 grams.

     Solution piperazine adipinata 5% for children (Solutio Piperazini adipinatis 5% pro infantibus). Contains 100 ml piperazine adipinata 5 g, 2 g citric acid, sugar syrup 72, 9 g, sodium benzoate 0.1 g, 20 ml of water. Transparent liquid poor yellow, odourless, oxygen sweet taste. One teaspoonful solution contains 0.25 g piperazine adipinata, dessert spoon - 0.5 g, dining spoon - 0.75 g.

     In enterobioze take in the same doses over 5 days from 7-day interruption; A 1 - 3 cycles of treatment. In between cycles to put on the night enema (for the removal of Ostritz rectal); Adults from 4 - 5 glasses of water, children from 1 to 3 cup with the addition of sodium gidrokarbonata, 1 / 2 teaspoon in a glass of water.

     Children can be ready to appoint 5% solution.

     When treating enterobioza be strict adherence to hygiene regime.

     Forms of piperazine adipinata : pills for 0.2 and 0.5 g; 5% solution (for children) in sklyankah orange glass of 100 ml.

     Storage :-pill under normal conditions; Solution in a cool place protected from the light.

     Rp. : Tab. Piperazini adipinatis 0.2

     N. 40

     D.S. On February 10 tablets per day (2 days) (adult)

     Rp. : Sol. Piperazini adipinatis 100 ml 5%

     D.S. At 2 table-spoon 2 times a day (2 days) (Child 12)

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