PIPOTIAZIN (Pipotiazine). Dimetilsulfamido-10- 2-[3-(4-oxides etilpiperidino) - propyl] - fenotiazin.

     Synonyms : Piportil, Piportil, Pipothiazine.

     On chemical structure similar to tioproperazinu differs from it in a side chain with nitrogen atom oksietilpiperidinil- propilnoy group instead metilpiperazinil- propilnoy.

     Has expressed and prolonged neuroleptic effects; Reduces psychomotor institute, the problem of fear, aggressiveness.

     When applied in the form of paranoid schizophrenia, gebefrenii, chronic psychosis with hallucinations, chronic delirium, and the mania attacks, the state of anxiety and other psychological disorders.

     Assign inwards in the form of tablets or drops for chronic psychosis and 20 - 30 mg per day for a time, after the stabilization - to 10-20 mg / day (out). In severe cases, appointed interior in the next few days to 30-60 mg / day, followed by 10 to 20 mg per day.

     After stabilization of the drug can be injected intramuscularly in the form of special medicinal form <<Piportil L 4>> (piportila palmitat);

     Piportil L 4 is the solution piportila palmitate (2, 5%) in the oil. The drug has a long, as the release of substances in the hydrolysis after injection. Solution impose intramuscularly 1 every 4 weeks. Intravenous introduction is not allowed. The average adult dose of 100 mg (4 2 ml, 5% solution). Older, epilepsy patients suffering from alcohol, mentally unstable originally imposed lower dose (25 mg), and then gradually increase the dose.

     Intramuscular introduction piportila L 4 allowed only after verification endurance drug (pipotiazina) when administered.

     Possible side effects, and precautions such as the treatment of other fenotiazinovymi Neuroleptics. When possible overdose parkinsonichesky acute respiratory syndrome and coma.

     The drug is contraindicated in agranulotsitoze, porphyria, zakrytougolnoy glaucoma; There may be a delay of urine in uretroprostaticheskih violations. For epilepsy patients to a lower threshold convulsant.

     Method of issuance : pipotiazin (piportil) issued yellow tablets of 10 mg (packing 200 pieces); A 4% solution in vials with a pipette to 10 ml (400 mg in vial). One drop of water-alcohol solution with 1 mg of active substance; Piportil L-4 in 2, 5% solution of oil in capsules to 4 and 1 ml (100 and 25 mg vials in). For injections are only glass syringes.

Materials allowed to copy only with the active hyperlink to the handbook of medicines