KVALIDIL (Qualidilum). 1, 6 Geksametilen- - bis - (3 benzilhinuklidiny chloride) tetragidrat.

     The white crystalline powder. The easily soluble in water and alcohol; The pH of aqueous 5, 5-7, 5.

     Antidepolyarizuyuschy muscle. Applied to relax muscles and controlled breathing in anaesthesia, may apply for tracheal intubations.

     Enter kvalidil intravenously. In dose of 1 mg / kg of the drug was relaxing muscles, continued for about 10 minutes, with some breathing oppression. Doses of 1, 2, 1, 5 mg / kg were miorelaksatsiyu, prodolzhayuaschuyusya 15 - 20 min, with a wave of patients is 4 to 5 minutes. Typically, this dose used when performing tracheal intubations using ditilin. Complete the muscle is the dose of 1, 8, 2 mg / kg, patients will continue to average 17 to 25 minutes. When dose 2 mg / kg muscles begin to relax by 1 / 2 to 2 minutes, a wave and full miorelaksatsiya occurred after 1, 5, 4 minutes.

     Withdrawal from kurarizatsii happening slowly : the emergence of self-breathing relaxation of muscles maintained for a period of 15 to 20 minutes; After 25-min PC muscle tone and breathing normally fully restored.

     For the first introduction kvalidil applied at the rate of 1, 2, 5 mg / kg.

     If necessary, extend to kvalidila his re-enter, reducing subsequent doses of 1, 5-2 times.

     In total operations of 1, 5, 2 hrs spent 200-220 mg drug.

     Neostigmine is kvalidila antagonist.

     Kvalidil not modify blood pressure, but it was a moderate tachycardia. A number of patients have increased salivatsiya and sweating; To reduce salivatsii introducing non atropine (0.2 - 0.3 ml of 0.1% solution). Some patients may be hyperemia front skin of the neck and upper torso half, which lies a few minutes.

     Contraindications and precautions are the same as for diplatsina. Like other muscle kvalidil apply only if indotrahealnom anaesthesia and with the conditions necessary for the tank. With regard to the development tachycardia should be carefully used in patients with cardiovascular disorders.

     Widespread use kvalidil no.

     Product : 2% solution in ampoules to 1; 2 and 5 ml pack of 10 vials.

     Storage : List A. In the dark spot.

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