ROOTS REVENYA (Radices Rhei).

     Collected fall or early spring aged at least three years, peeled, cut into parts dried roots and rhizomes cultivated in our country tangutskogo rhubarb (Rheum palmatum L., var tanguticum Mah im) long herbaceous plants, herewith. grechishnyh (l Ro from gona with e r).

     The roots and rhizomes contain rhubarb antraglikozidy, tanoglikozidy, hrizofanovuyu acid residues, dyes and other substances.

     Antraglikozidy are efiropodobnymi compounds, which after removal of sugar a emodin and other derivatives anthracene. Total derivatives anthracene in rhubarb roots of at least 2% (in terms istizin).

     The main active substances are emodin (trioksimetilantrahinon) and hrizofanovaya acid (dioksimetilantrahinon). They irritate interoretseptory intestines and cause increased peristalsis, providing the predominant influence on thick intestines and causing more rapid emptying.

     Purgative effects after taking the drugs rhubarb comes through 810 hours Slow effect and the dominant influence on thick ulcers usually explain that the break-in the gut antraglikozidov happens gradually and existing substances accumulate in number for poslablyayuschego effect only when they reach ablation. Thick mucous membranes large bowel most sensitive and responsive to such concentrations emodina that are not responsive receptors thin intestines. In addition, antraglikozidy after blowing in a thin intestines into the body of emodin, who appeared as thick gut and makes it peristaltiku.

     Drugs rhubarb appoint powder, pill, heroin, alone and in combination with other substances as softeners mainly with chronic constipation (usual). Usually, they are recommended for a night, well transferred and do not violate the intake processes and the smooth operation of thin intestines. Contained in the plant residues of substances can have some irritating effect on the bowel.

     Sometimes drugs are rhubarb in small doses (0.05 - 0.2 g) as a binder of less peristaltiku intestines. Their bonding due to the presence tanoglikozidov that, contacting proteins, besieging them, forming sludge, which protects the mucous membrane receptors.

     When taken drugs rhubarb urine, sweat and milk in nursing mothers stained yellow (presence hrizofanovoy acid), rolling when adding alkali in the red (oksimetilantrahinonov education).

     Applied following drugs rhubarb.

     Rhubarb Powder (R ulvis radicis Rhei). Powder yellow-orange or red. Hrustit of teeth because of calcium oxalate crystals. Assign of powders and tablets : adult-to 0.5-2 g / reception; Children 2 years - 0.1 g, 3 to 4 years - 0.15 g, 5-to 6 - 0.2 g, 7-9 years 0,25 - 0,5 g, 10 - 14 - 0.5-1 in children under 1 year is not appointed.

     Pills rhubarb (Ta bulett s and r dicis Rhei). Pills yellow brown color. Forty of 0.3 or 0.5 g of finely rhubarb root.

     Rhubarb dry extract (Eh tr you tum Rhei siccum). Water alcohol extraction. Major powder yellowish brown color, a distinctive smell, taste bitter. Since water is acidic solution mutnovaty reaction. Contains at least 3% anthracene derivatives. Dose depending on the age, from 0.1 to 1 to 2 grams per reception.

     R p. : T ab. rad. Rhei 0.5 N. 10

     D.S. At one pill two times a day (for food)

     R p. : R ulv. rad. Rhei

     Ma gnesii ohu di aa 0.3

     Yeh tr. Ve ll of a d nn s 0,015

     M.f. ulv s. ..

     D.t.d. N. 10

     S. On January powder 2 - 3 times a day

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