RANITIDIN (Ranitidine) *.

     N-[2-[[[5 - (Dimetilamino) methyl] furfuril] thio] - ethyl] - N '- methyl nitro-1, 1 ethylenediamine.

     Synonyms : Atsilok, Peptoran, Ranigast, Ranisan, Ulkuran, Acidex, Acilok E Anistal, Danitin, Istomar, Peptoran, Ranacid, Ranigast, Ranidil, Raniplex, Ranisan, Ranisen, Ranx, Taural, Ulcoren, Ulcuran, Ulsal, Vizerul, Zantac et al.

     Ranitidine is an antagonist of N-2 receptors. As of close to tsimetidinu. Making contact with the H 2-receptor parietalnyh gastric mucosal cells, and inhibits basal and stimulirovannuyu gastric secretion, the secretion of hydrochloric acid and enhancement.

     The drug is rapidly absorbed by ingestion. Peak concentrations in plasma after a single admission is 1 to 3 hours Length inhibition secretions of 8 - 12 hours Provided kidneys, mainly unchanged, partly in the form of metabolites.

     Indications for use are the same as for tsimetidina. According to reports, ranitidine more efficient and better shifts than tsimetidin. Effective in smaller doses than tsimetidin.

     Assign an adult typically 150 mg (one tablet) two times a day (morning and evening), regardless of meal times; With Zollinger-Ellison Syndrome-1 pill three times a day. Duration of treatment ranitidine 4-8 weeks.

     Adequate experience with the children until recently, did not exist, so they are encouraged to nominate their children under the age of 14 years.

     Ranitidine moved relatively well, side effects were less frequent than in the application tsimetidina, may, however, headache, dizziness, constipation or diarrhea, nausea, in rare cases, skin rashes, liver function violations.

     If violations are taking medication kidney function in smaller doses of 150 mg per night.

     The drug should not be appointed in pregnancy and breastfeeding.

     Unlike tsimetidina ranitidine does not significantly affect the function of the liver and dezintoksikatsionnuyu not potentsiruet of kumarinov, difenina, diazepam (sibazona) and other medicines.

     Product : pills to 0.15 g (150 mg).

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