RIBAMIDIL (Ribamidil). 1-b -D- Ribofuranozil-1 H-1, 2, 4-triazol-3- karboksamid.

     Synonyms : Virazol, Ribavirin, Ribavirin, Tribavirin, Viramid, Viratek, Viratel, Virazide, Virazole, Virustaz.

     The white with a yellowish sheen crystalline powder. The easily soluble in water, dry in alcohol.

     Ribamidil like edition, is a synthetic nukleozidom with antivirus activity. Ingibiruet synthesis of viral RNA and DNA.

     Passing through the cell membrane, ribamidil metabolised, becoming mono-and trifosfat. Ribamidil-5- monofosfat a competitive inhibitor inozinmonofosfata Dehydrogenase, leading to brake synthesis of viral RNA and DNA, is not acting on the host cells.

     Ribamidil provides antivirus application with influenza type A and B infections caused by herpes virus (herpes gingivostomatit, genital herpes, herpes zoster), as well as measles and chicken pox, hepatitis A and acute hepatitis B.

     Is inside (after eating). Doses for adults to treat influenza to 0.2 g 3 - 4 times a day for 3 to 5 days. Treatment should begin as early signs of disease. In other viral diseases appoint 0.2 g 3 - 4 times a day for 7 - 10 - 14 days. When treating severe infections may be nominated in one-day shock dose-1, 4 - 1, 6 g (1400-1600 mg).

     Children are at 10 mg / kg per day.

     In applying the drug can stomach pain, flatulence, increased indirect cium blood.

     Contraindications : acute liver and kidney disease, thyrotoxicosis, pregnancy.

     Product : pill (white with a yellowish sheen) to 0.2 g in a package of 20 pieces.

     Storage : List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines