ROFEKOKSIB (Rofecoxib).

     4-[4 - (Metilsulfonal) phenyl] -3 - fenilfuran-2 (5 H), he said.

     Synonym : Vioks, Viox.

     Provides blood and antiinflammatory effects.

     Bioavailability is 90%, S-max 2-3 h, T1 / 2 to 17 h; Biotransformation are in the liver, kidneys available mainly in the form of metabolites.

     When applied osteoartritah and acute pain syndrome (dismenoreya with dental and orthopedic operations).

     Assign inside of 0,0125-0,05 g (12,5-50 mg), 1 per day.

     Possible side effects : neuralgia, bronchitis, drowsiness, hallucinations, increased blood pressure, rarely ultserogennoe effect, peripheral oedema, fatigue.

     Method of issuance : pills to 0.0125 and 0.025 g (12.5 and 25 mg) (No. 7, 14); 0.25% and 0.5% suspension for receiving inside bottles of 150 ml.

     Storage : List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines