ROKSITROMITSIN (Roxithromycin).

     Synonyms : OBD Rocks, Brilid, Roksibid, Roksid, Roksimizan, Roksitem, Rulid, Rulitsid, Rulitsin, BD-Rox, Roksid, Roximisan, Roxitem, Roxybid, Rulicin, Rulid.

     Semi antibiotic similar to the structure of erythromycin - eritromitsin-9- [O - (2-methoxy) - methyl] oksim.

     It has a wide range of antibacterial action. Active against staphylococcus, streptococcal meningokokkov, enterokokkov, cholera vibrio, kampilobaktera, Chlamydia, klostridy, helikobaktera, legionell, listery, mycoplasms etc. force microorganisms, produce and produce penitsillinazu.

     It has also anti properties (suppresses synthesis Cytokines).

     Rapidly absorbed in the digestive tract (kislotoustoychiv), C max is 1,5-2 h, T? 10-14 h; well into the tissue and body fluid and penetrates into the spinal fluid; partially exposed biotransformation, allocated mainly to slow faeces.

     Applied with respiratory tract infections, ear organs (tonsillitis, pharyngitis, sinusitis, diphtheria, whooping cough, ear), the genitourinary system (Urethritis than gonoreynogo, adnexitis, tserviko- vaginitis), oral cavity (periodontit, periostit), skin and soft tissue , chronic osteomyelitis, migratory erythema, to prevent meningitis and other infectious diseases.

     Assign inside (to food) for adults to 0.3 grams a day (1-2 admission), children at the rate of 5-8 mg / kg / day (2 admission).

     For prevention of infection with AIDS apply to 0.3 g three times a week.

     The course of treatment for 5-12 days with acute respiratory and ear organs to 2-2,5 months with chronic osteomyelitis.

     Possible side effects : nausea, vomiting, diarrhea, disruption of the liver, increased pancreatitis, visual and olfactory, noise in the head, candidiasis, allergic reactions, etc.

     Contraindications to antibiotikam- of hypersensitivity to macrolides, in violation expressed in liver function, pregnancy and breastfeeding.

     Product : pills to 0.05; 0.1; 0.15 and 0.3 g (N. 10).

     Storage : List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines