SFEROFIZIN (Sphaerophysinum).

     Sferofizin - asexual, isolated from plants sferofiza salt (Sphaerophysa salsula Pall. Dc). , Herewith. pulses (Leguminosae), produced in Central Asia, Siberia, the Altai.

     Available as benzoate (Sphaerophysini benzoas). 1-Guanidino-4- (izoamilen-1- mud amino) - butane dibenzoat.

     The white crystalline powder odourless, bitter taste. The easily soluble in water (1:2), alcohol (1:3, 5), the solutions of caustic alkali and hydrogen. Aqueous solutions are sterilized at+  100 C for 30 min.

     Sferofizin has ganglioblokiruyuschey activity (see Ganglioblokiruyuschie drugs). One of the characteristics of the drug is its stimulating effect on the uterine musculature.

     Applied sferofizin in obstetric practice with a weak labor activity, krovotecheniyah and in the postpartum period atoniyah uterus as a means of accelerating the development of the uterus, and otherwise help stop bleeding. It may be used for maternity suffering hypertension and arteriosclerosis, when pituitrin contraindications.

     To promote labor activity imposed under the skin or intramuscular injection of 1 mL 1% solution repeated at 1 h; Only 6 injections. Inside appoint 0.03 g again in 2 hours

     In connection with the anti-hypertensive effect sferofizin sometimes used to reduce the AD in hypertensive stage I and II.

     Assign inside of 0.03 g 2 - 3 times a day under the skin or muscles to 1 ml of 1% solution (also 2 - 3 times a day).

     Product : powder.

     Storage : List B. The well ukuporennyh banks orange glass in the dark spot.

     Longtime structure and actions to sferofizinu synthetic drug izoverin (Isoverinum) excluded from the range of medicines as a relatively inactive.

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