Sidnofen (Sydnophenum). 3-(b-Fenilizopropil) - sidnonimina hydrochloride.

     White or white poor yellowish sheen melkokristallichesky powder, odourless, bitter taste. The easily soluble in water, soluble in alcohol.

     Synonym : Feprosidnine hydrochloride.

     Sidnofen fenilalkilsidnoniminov belongs to the group and is close to a structure sidnokarbu (see).

     As sidnokarb, sidnofen has a catalytic effect on the central nervous system, but losing in this sidnokarbu but has expressed antidepressant activity, which makes it a valuable product for the treatment astenodepressivnyh states.

     Antidepressive Effects sidnofena can be attributed to its ability to provide a reversible ingibiruyuschree impact on the level of MAO. It reduces the effects deprimiruyuschie rezerpina increases of epinephrine and noradrenalina, is a moderate increase in blood pressure. Has antiholinergicheskoy activity

     Applied with Pichinde of various origins, with adinamii, weakness, despondency, apathy on the neurosis, after an neyroinfektsy disease and endocrine glands (hypothyroidism, addisonizm etc.), with narcolepsy, pathological tiredness, as well as simple depression, depression with the slowing of the tsiklotimii and other testimony to the use of incentives and <light> antidepression funds

     Assign inside to food, starting with 0,005 grams (5 mg), 1 to 2 times a day; If necessary, increase the dose, adding to 5 mg / day every 2 - 3 days to 0,02 - 0,03 g day. Upon reaching the therapeutic effect of gradually reducing the dose. Supporting dose (if necessary long-term care) is normally 0,005 grams per day.

     When heavy dose of Pichinde sindnofena could be gradually increased to 0,06 - 0,08 g (in hospital).

     Is sidnofen morning.

     In applying the drug can raise blood pressure, headache, dry mouth, pain in the heart, rarely allergic itch. In these cases, we must reduce the dose or take a break in receiving the drug.

     In rare cases may occur <irony> reaction - sedative effect.

     Sidnofen contraindications patients with anxiety-depressive states (possible increased anxiety, increased gallyutsinatorno- officer syndrome). Sidnofen not be used in conjunction with antidepressants MAO inhibitors and tricyclic antidepressants. Between sidnofena of antidepressants and the groups as well as between antidepressants and sidnofenom must respect a break of at least a week.

     Product : pills to 0,005 grams (5 mg).

     Storage : List A. In the dark spot.

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