TEYKOPLANIN (Teicoplanin).

     Synonym : Targotsid, Targocid.

     Antibiotics isolated from the culture Actinoplanes teichomyceticus.

     For machinery and spectrum antibacterial action, indications for use and possible side effects similar to vancomycin. Better than itself against Staphylococcus aureus, and streptococcal enterokokkov, but losing against koagulazootritsatelnyh staphylococcus; A longer half-blood plasma (40-150 hours) and less cause side effects.

     After intramuscular a well absorbed, about 90% bioavailability, very slowly into the organs and tissues; Devoted mainly kidneys.

     Applied intravenous (drip), or intramuscularly.

     Adults initially appointed to 0.4 g intravenously 1-2 times daily for 1-3 days, then 0,2-0,4 g per day intravenously or intramuscularly; When psevdomembranoznom Colitis-to 0.2 g 2 times day; with burns and endocarditis-to 12 mg / kg per day. Children aged 2 months to 16 years, injected dose of 10 mg / kg 3 times at intervals of 12 hours, then 6-10 mg / kg one time a day intravenously or intramuscularly.

     Contraindications through breastfeeding.

     Product : dried powder for injection solutions in bottles of 0.2 and 0.4 g.

     Storage : List B.

Materials allowed to copy only with the active hyperlink to the handbook of medicines