TETATSIN- Calcium (Tetacinum-calcium).

     Dinatrievaya calcium salt of ethylene acid.

     Synonyms : Sa lcium disodium, Chelaton, Edatacal, Edathamil calcium disodium, EDTA, Mosatil, Natrii calcii edetas, Sodium edetate calcium, Tetraceminum, Versenate calcium disodium, etc.

     Available in a 10% solution for injection (Solutio Tetacini- sa lcii 10% pro injectionibus). Colorless transparent liquid; PH 5, 0, 7, 0.

     Tetanin- calcium (P aNa 2 EDTA) is a complex-compound. This cyclical complex compounds, which can replace calcium metal ions with the formation of low water-soluble compounds quickly removed from the body. Calcium can only filled with ions of metals, which are more stable than himself; These include lead, thorium and other ions with barium, strontium and other constant stability is smaller than the calcium in calcium tetatsin- the interaction does not.

     Applied in acute and chronic poisoning and heavy rare earth elements and their compounds (lead, cadmium, cobalt, mercury, uranium, yttrium, cerium, etc.).

     Assign inside and intravenously.

     Intravenous drip method introduced in isotonic sodium chloride solution, or 5% glucose solution. Under the dose of 2 g (20 mL 10% solution), four daily contact with a 2 times a day between infusion should be no less than 3 hours Enter daily for 3 to 4 days, followed by a suspension of 3 - 4 days. 1 month course of treatment.

     To handle the inside (with chronic lead poisoning and other heavy metals) can be applied pill, containing 0.5 g tetatsinkaltsiya. Assign a day to 2 g of the drug (0.5 g for 4 times or eight times 0,25 g), regardless of the meal. Is medication through 1 or 2 days (April 3 times a week), treatment continued 20 to 30 days; On course take 20 grams or more (but not more than 30 grams). Compared with intravenous treatment tablets a slower therapeutic response (elimination of lead cramping is a 7 - 10-day treatment).

     If after treatment is continuing contact with the lead and again showed symptoms of intoxication, it may repeat treatment tetatsin- calcium tablets, but not earlier than one year.

     Tetatsin- calcium is not suitable for jade, principally, liver diseases violation of its functions. There are indications that the use of large quantities of the drug (50-60 grams) can cause irregularities in the gastrointestinal tract and kidneys (Toxic argued). During treatment can decrease of hemoglobin in the blood, iron and Vitamin V 12.

     In acute food poisoning metals a drug only after a thorough cleaning of the gastrointestinal tract (stomach washing, mechanized enema.) . Note that formed when the tetatsin- calcium complexes with metal and can easily soluble absorption from the gastrointestinal tract, increasing phenomenon intoxication.

     In the process of treatment are encouraged to nominate ferrous inside and Vitamin V 12 (5 - 6 injection of 100 µ g daily).

     Method of issuance : 10% solution in 20 mL ampoules in a package of 10 vials.

     Storage : in the dark spot.

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