TETRATSIKLINA HYDROCHLORIDE (Tetracyclini hydrochloridum).

     Synonyms : Ambramycin, Amracin, Polfamycine, Tetracyclinum hydrochloricum.

     Tetracycline is different from tetracycline hydrochloride (s), better solubility in water. It may be used intramuscularly in order to put into cavities, local, as well as inside.

     The yellow crystalline powder bitter taste. Soluble in 10 parts of water and 100 parts 95% alcohol.

     Indications for use are the same as for tetracycline (s). For intramuscular injections usually resort to serious infectious diseases, which require rapid development of high blood concentrations of the drug (sepsis, peritonitis, infectious complications of surgical patients and others), and if the receiving drugs inside difficult or impossible (for vomiting, operations in the oral cavity and gastroenteric tract, with unconscious patient, etc.).

     To prepare the injection solution immediately before use, the contents of a bottle of breeding tetracycline hydrochloride (0.1 g) in 2 - 5 5 0 mL sterile solution (1 to 2%) novocaine. Injections produced in the upper outer quadrant of the buttocks; When she enters the solution under the skin reaction can be sensitive.

     For entry into the abdominal cavity dissolve the contents of a bottle (0.1 g) in 40 ml, and to introduce other cavities in 20 ml of 0.5% solution of novocaine.

     Under the adult dose intramuscularly 0.05-0.1 g (50000 - 100000 ED). Children aged between 8 and 10 years imposed on the 0.05 g, 10 - 14 years - to 0.06 g. injections produce 2 to 3 times a day for 5 to 7 days. If necessary to repeat cycles with intervals 4 to 7 days.

     Under the dose to give cavity (chest, abdominal) is 0,025-0.1 g.

     In DERMA, otorinolaringologicheskoy, ophthalmic practice medicine can be used as a juvenile.

     Inside designate tetracycline hydrochloride tablets in the same doses as tetracycline (s).

     Possible complications and contraindications are the same as in the application of tetracycline (s). Violations of the gastrointestinal tract, slightly less expressed in the intramuscular application of tetracycline hydrochloride.

     In the case of persistent infiltrates after intramuscular injection of cease.

     Method of issuance : in vials of 0.1 g (ED 100000); Pill-coated (red), at 0.1 and 0.25 g.

     Storage : List B. In dry, the dark place at room temperature.

     The so-called "Amratsin" (A mra with in) issued abroad in the form of ointments for a DERMA (3%) and eye (1%) practice in tubes of 10 and 5 g.

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