TETRATSIKLIN (Tetracyclinum).

     Synonyms : Deshlorbiomitsin, Achromycin, Cyclomycine, Deschloraureomycin, Hostacyclin, Panmycin, Polycicline, Steclin, Tetrabon, Tetracyn and others.

     The yellow crystalline powder odourless, bitter-tasting. Very little is soluble in water, it is difficult to alcohol. Resistant to slightly Wednesday, easily destroyed in solutions of strong acids and alkalis. Storage on the night light. Gigroskopichen. Has the ability lyuminestsirovat custody of blue and purple rays.

     Diffuses an antimicrobial substances, produced by Streptomyces and urefaciens or other relevant organisms.

     Tetracycline applied inside and External. Inside designate patients pneumonia, bronchitis, pleurisy Purulent, septic subacute endocarditis, bacillary and amoebic dysentery, whooping cough, flu, fever, gonorrhea, brucellosis, tularemia, typhus and typhoid return, psittakozom in infectious diseases urinary tract, chronic cholecystites, meningitis and meningitis in other infectious diseases caused by microorganisms, sensitive to the antibiotic. Diffuses can also be used to prevent infectious complications in surgical patients. Locally appointed tetracycline eye with infectious diseases, burns, phlegmon, mastitis, etc.

     There is a significant performance tetracycline with cholera.

     Diffuses and others in the series used to treat gonorrhea.

     When heavy septic infections tetracycline can be used along with other antibiotics.

     Assign inside (tablets) during or immediately after eating.

     Dose Adult 0.2 - 0.25 g 3 - 4 times a day (?high water). Children over 8 years appoint a daily dose of 20 to 25 mg / kg. Assign an adult drug in doses less than 0.8 grams a day should not, because, in addition to the lack of therapeutic effect may sustainable forms of microorganisms.

     In severe disease course, it would be better to start by injecting drugs tetratsiklinovoy group tetracycline hydrochloride or oksitetratsiklina hydrochloride.

     The course of treatment is on average 5-7 days. Once the symptoms of the disease, continue to take medication for 1 to 3 days.

     Diffuses usually well, but, like other antibiotics with a broad spectrum antibacterial action can cause side effects : reduced appetite, nausea, vomiting, disturbed bowel function (light or heavy diarrhea), changes in mucous membranes mouth and gastrointestinal tract ( glossit, disease, gastritis, proktit); there may be allergic skin reactions, swelling Kvinke etc.

     Diffuses and other drugs that can increase the number of skin sensitivity to the direct sunlight (photosensitization).

     It has been observed that prolonged use of tetracycline and other drugs in this group at the founding of the teeth (appointment children in the early months of life) can be the cause of children a dark yellow colour teeth (sediment preparation in tooth enamel and dentine).

     With long-term use of drugs tetracycline group could be complications arising from the development of candidiasis (skin and mucous membranes, and septicemia caused by the fungus drozhzhevidnym S andida a lbicans). For treating candidiasis-containing antibiotics used (see Nystatin, Levorin).

     During treatment tetracycline should carefully monitor patients. If signs of sensitivity to the drugs and side effects, make a break for treatment if necessary appoint another antibiotic (not from the tetracycline group); When events candidiasis designate pritivogribkovye antibiotics, vitamins.

     Diffuses contraindicated in sensitivity to him and to his family antibiotics (oksitetratsiklinu, doxycycline, etc.), with fungal diseases. With caution should be used in the preparation of kidney diseases and radiation. There should be appointed tetracycline (and others in this group) pregnant women and children under the age of 8 years.

     Recently, the prevalence tetratsiklinoustoychivyh strains of microorganisms and frequent side effects, the use of tetracycline has been relatively limited.

     Method of production : tablets, coated (red), to 0.05 g (50000 ED); 0.1 g (ED 100000) and 0.25 g (250000 ED) in a package of 20 pieces; Eye ointment .

     Diffuses and others to keep the group with caution (list B) in a dry, the dark place at room temperature.

     Ointments tetratsiklinovaya Eye (Unguentum Those tr Asous lini op hth and lmicum). Ointments yellow. It contains 0.01 g (10000 ED) tetracycline 1 g (1%).

     Applied with trachoma, conjunctivitis, blefaritah and other infectious diseases eyes.

     A century for the bottom 3 to 5 times a day.

     Product type : the aluminium tubes to 3; 7 and 10 g.

     R p. : Ung. Those tr Asous lini op hth and lmici 10.0

     D.S. Eye ointment. Lay down for centuries 3 - 5 times a day

     Ointments ditetratsiklinovaya Eye (Unguentum Ditetr Asous lini op hthalmi with um). Ointments yellow-brown color. Contains ditetratsiklina 1, 1429 grams tserezina, vaseline medical, oil vaseline to 100 g.

     Ditetratsiklin is N, N'dibenziletilendiaminovoy salt tetracycline. In connection with dibenziletilendiaminom (see also Bitsillin-1) is formed product, and has slowly vsasyvayuschiysya prolonged action. In laying in konyunktivalny bag for a period of 48-72 hours

     Applied primarily with eye infections requiring long-term treatment (trachoma, destruction of infected cornea, etc.).

     Ointments for a lower age 1 every day.

     Product : in tubes on 3; 7 and 10 g.

     Ointments tetratsiklinovaya 3% (Unguentum Those tra resources lini 3%). Ointments yellow. Includes 1 g 0.03 g (30000 ED) tetracycline hydrochloride. Applied to skin diseases : get rid, streptostafilodermii, abrasions, tinea infected eczema, ulcers and other trophic

     Ointments cause to areas affected 1 to 2 times a day or use as bandages, removable through 12-24 h. Duration of treatment for a few days to 2 to 3 weeks.

     In the case of itching, burning, skin treatment ceased.

     Product type : the aluminium tubes to 5; 10; In 30 and 50 g.

     Storage : Keep in a cool place.

     Tetracycline and nystatin tablets, coated (T abulettae Those tra resources lini et Nystatini on bduct s). Forty 0.1 g (ED 100000) 100000 ED tetracycline and nystatin.

     Assign with testimony to the use of tetracycline. Adding Bean antibiotic nystatin aims at the development kandidamikoznyh infections (see Nistatin). Dose set on the basis of the drug in the tetracycline.

     Product : pills in banks orange glass on 10 and 25.

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