TETRINDOL (Tetrindolum). 2, 3, In, 4, 5, 6-1 H Geksagidro-8- Cyclohexyl pirazino (3, 2, 1-j k) karbazola hydrochloride.

     White with yellow or yellow - greenish white crystalline powder. Almost nerastvorim in water, soluble in alcohol little.

     According to the chemical structure similar to tetrindol pirazidolu, is a situation in 8 pirazinokarbazolovogo kernel tsiklogeksilnogo radical group SNz instead.

     By pharmacological properties tetrindol close to pirazidolu. It is also reversible kratkodeystvuyuschim selective MAO inhibitor type A. The product is actively inhibited dezaminirovanie noradenalina and serotonin and less tiramina that virtually removing the risk of development <<column>> (tiraminovogo) syndrome.

     Tetrindol not have holinoliticheskogo action. Like pirazidolu weakens deprimiruyuschie effects rezerpina, potentsiruet effects fenamina, L-dofa, 5-oksitriptofana.

     The product is quickly absorbed in the employment inside easily permeates through cross the blood-brain barrier, is found in brain tissues in relatively high concentrations.

     An important feature of the therapeutic tetrindola a quick offensive impact. Unlike other antidepressants, and the impact is through the 7 - 10 days later, the tetrindola through a 2 - 3 days from the start of treatment.

     In the spectrum of tetrindola coupled catalytic (psihoenergeziruyuschee) and the actual antidepressant (timolepticheskoe) influence.

     Preparation designate various dysfunction in depression: endogenous and psychogenic (reactive, nervous), depression resulting from organic brain defeats, in violation of depressed patients of chronic alcoholism.

     Application tetrindola preferably with the depressed state of tsiklotimicheskogo level (simple melancholic syndrome, and Pichinde adinamicheskie disorder, and depression with ideatornoy engine block, depressed violations predominantly ipohondricheskoy STDs).

     The clinic tetrindol alcohol use in astenodepressivnyh condition, adinamicheskih subdepressiyah, of ongoing low mood, despondency, apathy, high fever, in the absence of expressed concerns, insomnia, disforicheskih violations, and outside acute abstinence.

     Assign tetrindol inwards in the form of tablets, from 0,025 doses of 0.05 g (25-50 mg) for admission, 2 times a day (morning and afternoon), with a gradual (within 1 to 2 weeks) increased dose individually as from the efficiency and portability to 0.2 - 0.4 g (200-400 mg) a day. Selection of the optimal dose, duration of treatment depending on the nature of the disease and over, the efficiency and portability products.

     Tetrindol usually moved well, including the sick and elderly old age. Lack holinoliticheskih properties to assign product with accompanying glaucoma, adenome prostate gland and other diseases, in which combination drugs antidepressants (amitriptyline, Imipramine) providing antiholenergicheskoe effect.

     In some cases, the treatment tetrindolom may exacerbate feelings of anxiety, drought in the mouth, headache. When receiving the drug in the evening possible violation of sleep. Complications, such <Cheese Marking> syndrome, using tetrindola virtually no.

     Tetrindol contraindications with inflammatory diseases of kidney and liver during worsening, as well as acute alcohol abstinence.

     Form release: pills to 0,025 and 0.05 g (25 and 50 mg), thickly coated pink coloured glass in banks of 50 pieces.

     Storage: List B. In a dry, sheltered from the world scene.

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