UROKINAZA (Urokinase).

     Synonyms: Purotsin, Ukidan, Purocin, Ukidan.

     Enzyme product derived from human renal cell culture.

     Unlike streptokinase is a direct plasminogen activator (finance and lizplazminogenov), making it plazmin. Urokinazy advantage of streptokinase is the lack of its antigenic properties.

     Apply mainly on the same grounds as streptokinase, mainly in poor portability last (allergic reaction).

     Enter intravenously and vnutrikoronarno.

     In acute myocardial heart attack on intravenous enter 2000000 IU (isotonic sodium chloride solution, or 5% glucose solution) bolyusno or 1500000 IU bolyusno with limited follow the same dose for 1 hour or vnutrikoronarno to 6000 IU per minute to the total dose 500000 IU.

     In deep vein thrombosis and pulmonary artery embolism impose intravenously to 4400 IU / kg over 10 min, followed by 4400 IU / kg per hour for 12-24 h.

     In peripheral arterial thrombosis enter intravenously to 250000 IU for 20 minutes, then 750000 IU over 12 hours

     Possible side effects and contraindications are the same as those of streptokinase.

     Form release: dried powder for injection solutions in vials of 100000, 500000 and 1000000 IU.

Materials allowed to copy only with the active hyperlink to the handbook of medicines