Ksipamid (xipamide)


KSIPAMID (Xipamide).
     Hlor-N- 4 - (2,6 - dimetilfenil) -3 - sulfamoilbenzamid.
     Synonym : Akvafor, Aquaphor.
     On the chemical structure and action close to indapamidu (the same applies to a group benzamidov; Instead indole Deputy contains dimetilfenilny Radical).
     Quickly and completely absorbed in the digestive tract, with max of 1 h, T? 7-h; biotransformation are in the liver, kidneys predominantly displayed.
     Applied as diureticheskogo and antihypertensive funds.
     Is inside (squeezed water) in a daily dose of 0.01 to 0.04 g 1-2 admission (to 0,06-0,08 g / day).
     Diuretichesky effect develops in 1 h after administration, reaches through a 3-6 hour and continues for 12-24 h.
     Possible side effects and contraindications such as the application of other salureticheskih diuretikov. Sometimes gipokaliemiyu cause.
     Product : pills to 0.01 and 0.04 g (N. 10, 20).

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