Ziksorin (zixorin)
ZIKSORIN (Zixorin). Triftormetil- a 3 - ethyl-benzhydrol :
Colorless oily mass.
Synonyms : Flumetsinol, Flumecinol, Synklit.
The drug induces oksidaznuyu mikrosom liver enzyme activity; Increased education glyukuronidov facilitates removal from the body of endogenous and exogenous metabolites increased allocation of bile. The preparation of mikrosomalnye enzymes acting on selectively expressed by other pharmacological effects will not help. 3 iksorin well absorbed by ingestion, is metabolized in the liver, are metabolites in urine and faeces with.
When applied in functional hyperbilirubinemia, in patients with chronic diffuse liver disease, and jaundice caused enzimopatiyami and dobrakachestvennym vnutripechenochnym cholestasis, and food allergies, accompanied by jaundice, as well as for the prevention and treatment of jaundice in the newborn.
There is evidence of the effectiveness of adjuvant therapy ziksorina skin diseases (psoriasis, atopic dermatitis) and chemotherapy patients.
Assign ziksorin adults (during or after eating) for chronic diseases of 0.4 - 0.6 g (4-6 capsules) one day a week or 0.1 g three times a day. The course of treatment two weeks. After a 2 - 4-week break might recurrence rate using the same dose or low, depending on the patient.
When newborn jaundice give 2-day life of 10 mg / kg / day for 3 to 5 days. To prevent jaundice in newborns, pregnant provide for 1 to 3 days before the expected birth 0.4 g (4 capsules) once.
When atopic dermatitis among children placed ziksorin 2 mg / kg in 1 - 2 admission.
In applying the drug may nausea, individual neperenosimost.
Please note that due to the induction of liver enzymes (see Phenobarbital) ziksorin may accelerate the metabolism of other drugs simultaneously.
Product : capsules to 0.1 g flumetsinola pack of 25 pieces.
Storage : in the dark spot.
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