Zolpidem (zolpidem)


ZOLPIDEM (Zolpidem).
     N, N-6 Trimetil-2- parameters tolilimidazo [1,2-a] pyridine acetamide (tartrate).
     Synonyms : Ivadal, Nitrest, Sanwal, Ivadal, Sanval.
     Swiss drug shorter duration. This improves the ability to fall asleep, increasing the length and quality of sleep.
     Rapidly absorbed in the digestive tract, bioavailability of about 70%, C max at 1.6 h, T 1 / 2 1,4-4,5-h; Kidney allocated in the form of inactive metabolites.
     Assign adults 20-30 minutes before sleep, dose 0,005-0,01 g (5-10 mg), older patients - 0,005 of the city Son is fast and normally lasts about 6 hours The course of treatment is not more than 4 weeks.
     Possible side effects : daily mood, anterogradnaya amnesia, diplopia, violation of behavioral reactions (akressivnost, hallucinations, etc.), sputannost consciousness, neuralgia, visually impaired skin allergic reactions, drug dependency (in long-term use).
     Contraindications : respiratory failure, male, a violation of the liver, depression, pregnancy, breast-feeding.
     Potentsiruet effects of narcotic analgesics, barbiturates, Neuroleptics, antidepressants, protivogistaminnyh drugs; Flumazenil eliminates sleeping pills to zolpidem.
     During drug treatment should not perform work requiring quick coordinated response (operator activities, driving, etc.).
     Product : pills to 0,005 and 0.01 g (5 and 10 mg) (7.10 N) /

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